Lawrence Foca, 73, of Manchester was traveling east at 9:10 p.m. Thursday when he went off the right shoulder, struck a sign and was ejected from his bike, Manchester police said.
The motorcycle kept going, overturning several times before slamming into a tree near Pleasant Valley Road, police said.
Foca was brought to an area hospital, where he was pronounced dead, police said.
He was wearing a helmet, they said.
The crash is under investigation.
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